CD52 anticorps

N° du produit ABIN320173

Cet anticorps Rat Monoclonal détecte spécifiquement CD52 dans FACS, WB, IHC (p), IHC (fro), CyTox, IP et EIA. Il présente une réactivité envers Humain et Singe.

Aperçu rapide pour CD52 anticorps (ABIN320173)

Antigène: CD52

Reactivité: Humain, Singe

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD52 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Cytotoxicity Test (CyTox), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: YTH34-5

Détail du produit anti-CD52 anticorps

Specificité: SM2135LE reacts with the Human CD52 antigen, also known as CAMPATH-1. Humanised versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies.

Purification: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

niveau d'endotoxine: Low Endotoxin

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry (1/50-1/100): Use 10 μL to label 1 x 10^6 cells in 100 μL. Immunohistochemistry (Frozen/Paraffin/Resin): This product does not require protein digestion pretreatment of paraffin section. However enhanced results may be seen using Trypsin protein digestion (2). ELISA. Western Blotting. Immunoprecipitation. Cytotoxic Assays (50 μg/mL): Use human serum as complement source.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS without preservatives or stabilizers.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD52

Antigène: CD52

Autre désignation: CD52 / CAMPATH-1

Sujet: The CD52 antigen is a remarkably small peptide that is heavily glycosylated, and attached to the cell surface membrane via a GPI link. The apparent molecular mass of the antigen on SDS-PAGE is 25-29kD. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

ID gène: 1043

NCBI Accession: NP_001794

UniProt: P31358